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doi: 10.1172/JCI31935 23 KingMRIsmailASDavisLSKarpDR

The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumour regression and attenuates mechanisms involved in invasion of uveal melanoma cells

378 In DA neurons, reduced expression of PGC-1 has been observed, suggesting that PGC-1 dysfunction may play a role in the clinical pathogenesis of PD