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Lin et al., 2014)

DKD patients exhibit significant structural dysbiosis of gut microbiota, characterized by decreased abundance of beneficial bacteria producing short-chain fatty acids (SCFAs) and increased abundance of harmful bacteria generating uremic toxin precursors (12)

Pharmacol Res 146:104332104346

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Cyclophosphamide is an antineoplastic, broad-spectrum anti-tumor and anti-cancer alkylating agent and is also used as an immunosuppressant for treatment of autoimmune diseases and in bone marrow transplants [8]