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Intensive Care Med 43:304377 Singer DB (1973) Postsplenectomy sepsis

With increased metabolism comes the faster breakdown and removal of fat from the body

M., Juul, S., Lauritzen, L., Nexo, E., and Ellegaard, J

A person with Beta Thalassemia Major is completely transfusion dependent from about 6-24 months of age requiring 2-4 units of blood every 15-30 days for survival apart from complex iron chelation to control the excess iron deposition due to the repeated blood transfusions and increased iron absorption caused by this ineffective red blood cell production