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J.AxonA

J Pharmacol Exp Ther (2002) 301(2):41826

Simple things like giving her the right food can make the difference between prolonged illness and a speedy recovery

This is achieved through a complex interplay of multiple mechanisms that involve Hcy metabolism, oxidative stress, neurodegeneration, and SAM-dependent epigenetic modifications

To confirm the presence of the SP3N-derived aldehyde (SP3CHO) and the dependence on FCS for this metabolic step, we treated KBM7 cells with SP3N in IMDM + 10% FCS or Opti-MEM without FCS and used ultra-performance liquid chromatography-mass spectrometry (UPLC-MS/MS) to detect the formation of the aldehyde species