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Griffin P

Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer

The small molecule drug CA-074-methyl ester reduces lipid peroxidation and mitochondrial dysfunction in macrophages by inhibiting cathepsin B, thereby alleviating ferroptosis and inducing polarization of M2 macrophages, promoting the recovery of nerve function in mice after SCI