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Japan K-8256,427

Ota N, Itani M, Aoki T, Sakurai A, Fujisawa T, Okada Y, Noda K, et al

In studies using human gingival and periodontal stem cells [4, 45], Epitalon enhanced the expression of: Nestin (neural progenitor marker) GAP43 (axon growth) -Tubulin III and Doublecortin (neuronal differentiation and migration) Together, these shifts suggest Epitalon may prime stem cells toward neuronal lineage, hinting at applications in regenerative neurology or brain injury recovery models

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VLK conceived the study, and participated in its design and coordination and helped to draft the manuscript