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Practical Gastroenterology

This infers that the raised inflammatory gene expression in cardiomyocytes observed in hyperglycemia is secondary to impaired repressive epigenetic histone modifications [200]

156 Besides, with the consumption of extracellular glutamine, GDH can also catalyze ammonia derived from glutaminolysis and -KG to support the synthesis of glutamate and downstream metabolites by reductive amination in a NADPH consumption manner to meet the cancer cells growth