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However, there are some precautions to consider

Both approaches commonly act on key signaling pathways, including Nrf2, NF-B, and AMPK, indicating a potential for synergistic interaction

Furthermore, our single-cell mass cytometry approach was limited to ~40 proteins, capping the number of metabolic pathways we could interrogate simultaneously

Conclusions Our findings reveal a growing trend toward digital integration in rare disease trials to support decentralized, scalable, and patient-centered research models