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Notably, two of the most important transcription factors coactivated by PGC-1 are Nrf2 (Nuclear Factor E2-Related Factor 2) and LXRs (Liver X Receptors) 16

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An oxidized dextran-composite self-healing coated magnesium scaffold reduces apoptosis to induce bone regeneration

In line, other evidence also revealed a relationship between oxidative imbalance and neuropathic pain (Di Cesare Mannelli et al., 2016)

Defective IL-12 production was also observed during Mycobacterium tuberculosis infection, in which diabetes is likewise known to be a strong risk factor