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Glu can also be produced by transamination of -ketoglutaric acid

For instance, Porphyromonas gingivalis exacerbates ALD by inducing hepatocyte ferroptosis, whereas interventions targeting the restoration of microbiota balance have shown therapeutic potential by suppressing ferroptosis

As bacterial fermentation products in the intestine, SCFAs can act as signaling molecules to regulate the physiological functions of intestinal epithelial cells and improve the host health [33]

Mutations in TSC1 or TSC2 lead to the development of tuberous sclerosis, a disease characterized by multiple benign tumors in several organs, hinting to its function in the growth-related mTORC1 pathway (Huang and Manning, 2008)