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Acute toxicity (dermal): category 1 (0 50 mg/kg), category 2 (LD 50 50 200 mg/kg) and category 3 (LD 50 200 1000 mg/kg) (Winder et al., 2005

However, host susceptibility is likely to have a relevant impact on the outcome of the studies and in this context, elements of stress and animal strain could have a profound impact on the outcome of the studies (Youdim et al., 2003