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Mechanistic investigations reveal a constellation of molecular mechanisms: downregulation of deoxycytidine kinase cripples drug activation, while ribonucleotide reductase overexpression replenishes nucleotide pools

Biomedicines, 8 (11), 522

( A ) The firing neurons during RSI in the WT_Water, Tbr1 +/ _Water, WT_Cocktail, and Tbr1 +/ _Cocktail groups were separated into two neuronal ensembles via within-cluster sum of squares (WCSS) analysis