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Neurogastroenterol Motil 23(8):697710 Taheri Y, Quispe C, Herrera-Bravo J, Sharifi-Rad J, Ezzat SM, Merghany RM, Shaheen S, Azmi L, Prakash Mishra A, Sener B (2022) Urtica dioica -derived phytochemicals for pharmacological and therapeutic applications

5 Our previous study had revealed that this quantitative expansion is accompanied by the functional activation of neutrophils, characterized by enhanced release of reactive oxygen species (ROS), increased formation of neutrophil extracellular traps (NETs), and elevated secretion of pro-inflammatory cytokines such as tumor necrosis factor- (TNF-)

FIGURE 3 Hypermethylation of ADHFE1 (Alcohol dehydrogenase iron containing 1) promotes the proliferation of CRC cells by regulating cell cycle progression (Hu et al., 2019)