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Although, the amount of vitC delivered into the upper dermis might exceed the upper range naturally found in dermis, no irritation was observed

4AC, Supplementary Fig

[Abstract] Stem Cell Res Ther

Tully DC, Rucker PV, Chianelli D, Williams J, Vidal A, Alper PB, Laffitte B (2017) Discovery of tropifexor (LJN452), a highly potent non-bile acid FXR agonist for the treatment of cholestatic liver diseases and nonalcoholic steatohepatitis (NASH)