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G., Joe E

doi: 10.1093/clinchem/47.8.1500

The BBB is present as a highly selective semi-permeable interface between blood and brain, possessing a defensive network of blood vessels and brain tissues that are complex, dynamic, and prevent the entry of harmful substances such as neurotoxic debris derived from blood, cells, and other microbial pathogens [6]

While the impact of lipid uptake on GSH levels remains unclear, our data strongly argue that an essential role of GSH/GPX4 in activated CD8 + T cells is to sustain their effector function and protect them from ferroptosis as opposed to redox buffering