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MUC1 activates PD-L1 transcription through recruitment of MYC and NF-B p65 to the PD-L1 promoter, thus enhancing immune evasion (223)

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Both in vitro and in silico experiments also showed lauric acids cytotoxicity towards murine macrophages, HepG2 (human hepatocellular carcinoma), and HCT-15 (human colon cancer) cells

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The results showed that ERK, JNK and P38 were all activated after MIRI (Figures 7A, B), among them, Sat1 inhibition only significantly suppressed the activation of MAPK/ERK, but Sat1 over-expression did not significantly promote the activation of MAPK/ERK (Figure 7B)