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The use of sdAbs such as [ 68 Ga]Ga-NOTA-Nb1053 allows same-day imaging one hour after injection with high target-to-background ratios, avoiding concerns associated with non-specific bone accumulation seen with 89 Zr-labeled mAb immunoPET techniques

Worse, doctors will often stop treatment altogether when blood levels seem okay

Oral supplementation works because approximately 1% of an oral dose is absorbed through passive diffusion, bypassing the need for intrinsic factor