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Assessment of liver fibrosis by transient elastography in rheumatoid arthritis patients treated with methotrexate

Moreover, in hepatocellular carcinoma (HCC), antiangiogenic tyrosine kinase inhibitors (TKIs) are effective therapeutic agents and the main therapeutic effect is to induce severe hypoxia in the tumor microenvironment (TME) through depletion of the vascular density of tumor

These reports indicate a downregulation of mitochondrial oxidative respiration, and a possible association to TORC1 repression, as we observed in CLN3 iPSC

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