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Drug-induced liver injury: pathogenesis, epidemiology, clinical features, and practical management

SchifferMvon GersdorffGBitzerMSusztakKBttingerEP

doi: 10.1016/j.pathophys.2016.10.001 142 RauchovHVokurkovMPavelkaSBehuliakMTribulovNSoukupT

A study evaluating EGCGs impact on nave CD4 + T cell differentiation showed that the green tea polyphenol inhibited Th1, Th9, and Th17 differentiation by downregulating the respective transcription factors T-bet, PU.1, and RORt, while also preventing IL-6-induced suppression of Treg development

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