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Similarly, other small molecule inhibitors and antibody-drug conjugates are being tested in other types of cancers where the IGF-1R/PI3K and AXL signaling pathways have also recently attracted attention, including in primary bone cancers where they play a major role in oncogenesis, cell differentiation and fate, metastasis, and drug resistance (53)

A randomized controlled trials evaluated the effect of a capsulated serum containing a mixture that includes vitamin E exhibiting antiaging and brightening effects of skin [176]

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Lutein may stimulate extracellular signal-regulated kinase (ERK, a mitogen activated protein kinase) and cause the dissociation of Kelch-like ECH-associated protein 1 (Keap1) from the Nrf2/Keap1 complex

This was solved once Collip found a way to remove contaminants from the extract