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Mechanisms of migraine as a chronic evolutive condition

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Glutamine, a nonessential amino acid, is the most common free amino acid found in body fluids and skeletal muscles and has a pivotal role in regulating cell proliferation and growth [30] as well as stimulating incretin hormones, particularly GLP-1 secretion [15]

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Common pathways implicated in these conditions include dysregulated lipid metabolism, oxidative stress, and impaired energy metabolism, reflecting widespread dysfunction in fundamental biological processes