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Body composition measurements (DEXA or even calipers) will show fat percentage dropping

Key Preclinical Study (Neelakantan et al., 2018): Treatment in diet-induced obese mice produced progressive body weight loss, reduced white adipose tissue mass and adipocyte size, decreased total cholesterol, and no changes in food intake effects were metabolic, not appetite-driven

This experiment confirmed that the product can delay systemic aging by regulating NAD+ metabolism, providing in vivo evidence for anti-aging interventions

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However, their specific roles in macrophage function, particularly in the context of immune regulation, remain elusive