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The brain uptake of one third of the reported (pro)drugs and nanocarriers was not investigated (Table II,III)

Although blood-based tau biomarkers have demonstrated high diagnostic performance, additional accessible biofluids may provide alternative molecular information and further support screening and disease monitoring strategies

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Merely two decades later, it became evident that the trajectory of illness serves as one of the most significant modifiers of the NIMETOX pathways, as well as the clinical phenomenology associated with MDD