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As suggested by Meister and Anderson (1983), Transport of GSH may protect the cell membrane against oxidative damage

10.1039/C6RA13075E 38 DayZ

Nonetheless, within tumor-bearing hosts, DCs often exhibit an immature and malfunctioning phenotype due to the limited tumor immunogenicity and the presence of immunosuppressive agents secreted by either tumor cells or tumor-associated immunosuppressive cells, thereby allowing tumors to evade immune surveillance [39, 40]

The assay involves carefully optimized enzymatic recycling method using glutathione reductase and Ellmans reagent (DTNB)

492 Mutant IDH abnormally accumulates D-2-hydroxyglutarate (D-2-HG), triggering epigenetic reprogramming and blockade of cell differentiation, which are particularly prominent in gliomas and hematological malignancies