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This is about visible transformation

Hepatology 46 , 20212031 (2007)

EZH2 inhibits autophagic cell death of aortic vascular smooth muscle cells to affect aortic dissection

232 Several studies have demonstrated that loss of function of UBE3A leads to increased ARC expression and subsequently decreases the number of AMPARs, ultimately impairing synaptic plasticity at excitatory synapses

For instance, p53 forms homotetramers such as STAT3, and CREB forms homodimers and heterodimers that bind to DNA and regulate transcriptional activity