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doi: 10.2174/156720510793499066 205 PinkiewiczM.ZaczynskiA.WaleckiJ.ZawadzkiM

Cyanocobalamin should not be used in patients who are pregnant and in patients with early hereditary optic nerve atrophy and cyanocobalamin hypersensitivity

Its FDA approval is built on this exact outcome, and the clinical evidence is robust

This creates a concentration of 500mcg/mL, which makes measuring common research doses (like 25mcg or 50mcg) very straightforward using a standard insulin syringe