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Tissue Repair and Fortification: The diverticula themselves are structural weaknesses

As chemotherapeutic drug currently in clinical use are cytotoxic drug, they all damage normal cells to varying degrees, and various toxic side effects (e.g

However, despite their cost-effectiveness and suitability for high-throughput screening, in vitro models cannot fully mimic intestinal absorption, enterohepatic circulation, or gut microbial metabolism, underscoring their inherent physiological limitations (Alminger et al., 2014)

doi: 10.1038/s41541-021-00391-8 242 SasaiM.YamamotoM