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Epigenetic regulation of sex-specific hepatic gene expression Another key factor influencing liver metabolism and HCC is epigenetics, encompassing global DNA hypomethylation of oncogenes, hypermethylation of tumor suppressors, histone modifications that alter chromatin accessibility, chromatin-loop rearrangements facilitating enhancerpromoter oncogenic interactions, and post-transcriptional regulation via microRNAs and RNA modifications [144]

doi: 10.24846/v30i2y202102 [DOI] [Google Scholar] Qiu S., Liu Q., Zhou S., Wu C

Currently, a more sophisticated one-pot method for in vitro tRNA synthesis has been developed (Korenci, Sll, and Ambrogelly, 2002)

[DOI] [PubMed] [Google Scholar] 80.Adam J., Hatipoglu E., OFlaherty L., Ternette N., Sahgal N., Lockstone H., Baban D., Nye E., Stamp G.W., Wolhuter K., et al

The role of s-nitrosylation and s-glutathionylation of protein disulphide isomerase in protein misfolding and neurodegeneration