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Proc Natl Acad Sci U S A 116(1):297302

Gastrointestinal Associated IBS Pathophysiology Alteration in Gut Microbiota Under normal circumstances, mucus epithelium barrier confines microbes to the epithelial surface or intestinal lumen where homeostatic immune responses are induced to maintain barrier integrity and tolerance among commensal microbes

Supplements were diluted in water containing TM (2 mg/ml) to stabilize the substances and simulate high carbohydrate intake

Conclusions This study establishes a novel and critical molecular mechanism for the pharmacological actions of BPC157, centered on the BPC157-FBXO22-BACH1 axis

A., Tapia-Mendoza E., et al