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This review is primarily concerned with discussing the recent understanding of redox signaling and gene regulation, the role of oxygenation in determining cell fate (apoptosis) and the downstream, protracted inflammatory state

Mechanistic studies reveal that inflamed intestinal tissues in IBD patients and corresponding animal models display characteristic ferroptosis features, including GSH depletion, suppression of GPX4 activity, and abnormal iron deposition

Uttamsingh V, Keller DA, Anders MW

[PMID:28964311] Densmore JC, Oldham KT, Dominguez KM, et al

Discussion 3D ET reveals distinct spherical vesicles in Arabidopsis root cells A longstanding question regarding plant retrograde transport concerns their origin, for which two distinct models have been proposed to date: (1) retrograde transport mediates the transport of VSRs from MVBs to the TGN, and (2) retrograde transport facilitates the transport of VSRs from the TGN to the Golgi and/or the ER