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Herein, we focus on the potential therapeutic effects of IGF-1 in NDD associated with MetS and the molecular mechanisms underlying its pharmacological effects

[PubMed: 10569383] (Retrospective analysis of patients admitted to four hospitals over 4 years

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To provide further mechanistic insight into the role of IGF-1/IGF-1R in NK cell development, we investigated the levels of IRS-1 in human CD34 + cells cultured with either IL-15 or the combination of IL-15 and IGF-1 at 14 or 21 days and compared it with the levels of IRS-1 in 293A cells, which usually expressed normal levels of IRS-1

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