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ERS Clinical Practice Guidelines (2025): The European Respiratory Society updated its management guidelines, issuing a conditional recommendation for the use of mucoactive drugs like NAC in specific NCFB phenotypes, particularly those with high sputum production and frequent exacerbations (94)

albicans with abnormal ergosterol synthesis, chloroquine also disrupts morphogenesis (Shinde et al., 2013)

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To further explore the effects of microbial metabolites on mitochondrial enzymes, molecular docking was used

In our study, the use of NAC, corticosteroids and enoxaparin were associated with lower mortality