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Asterisks indicate neutral loss of phosphoric acid (H 3 PO 4 , 97.98 Da), which is commonly observed for phosphoserine- and phosphothreonine-containing peptides upon HCD fragmentation

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The initial treatment regimen for patients without neurological involvement typically consists of hydroxocobalamin 1mg intramuscularly three times weekly for two weeks, followed by maintenance injections every two to three months for life