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Ghrelin and Control of Energy Balance Control of energy balance through two types of neurons of the arcuate nuclei: (1) Proopiomelanocortin (POMC) neurons that release amelanocyte- stimulating hormone (-MSH) and Cocaineand Amphetamine Regulated Transcript (CART), reducing food intake and increasing energy expenditure

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In the first experiment, we inactivated Ube3C using IUE of Cre into E14.5 cortical progenitors in Ube3C f/f mice, followed by intraperitoneal administration of 5-bromo-2-deoxyuridine, BrdU, eight hours post-operation (Fig