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Additionally, TFRD reduced MDA and ROS levels in the serum and the expression of Notch1, Hes1 and PRDX1 proteins in femur tissues, suggesting that TFRD plays an anti-osteoporosis role by inhibiting the activation of the Notch1/Hes1/PRDX1 signalling pathway, alleviating oxidative stress injury, inhibiting osteoclastogenesis and bone resorption, promoting bone formation and regulating bone homeostasis

The therapeutic efficacy of Lorazepam in preserving spinal cord integrity underscores the clinical potential of targeting pH-sensing GPCRs in ischemia-reperfusion pathologies

Effect of hyperglycemia on purinergic and nitrergic inhibitory neuromuscular transmission in the antrum of the stomach: implications for fast gastric emptying

Given the rapid and dynamic nature of MDV biogenesis, researchers have developed innovative experimental approaches to dissect the molecular composition and functional roles of these vesicles under various metabolic conditions