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35 Cigarette smoke-induced oxidative stress plays role in enhancing inflammation by regulating redox-sensitive transcription factors, such as nuclear factor kappa-B (NF-B) and activating protein 1 (AP-1), the extra-cellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK), and p38 mitogen-activated protein kinase (p38MAPK) pathways

Pharmaceutics 15 (8), 2071

Improves peripheral circulation

Study population This study included 92 patients with migraine recruited from outpatients referred to Imam Mousa Sadr Clinic, belonging to Isfahan University of Medical Sciences, Isfahan, Iran, from November 2020 to March 2021

Studies have shown that dyspnea in asthma patients can trigger abnormal activity in brain regions involved in emotional regulation (e.g., the insula), leading to a reduced emotional control capacity and a predisposition to anxiety and depression [71, 459]