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Phase 2 data showed up to 60% of participants at higher doses reported at least one gastrointestinal symptom

Immunopharmacology 41 , 7787 (1999)

Due to the natural variability in vitamin B 2 levels in plant-based ingredients, along with factors that affect bioavailability and potential degradation, supplementing with fermentation-produced riboflavin through premixes is necessary to meet the vitamin requirements in pig nutrition [17, 38]