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Description

The Glutathione System of Peroxide Detoxification Is Less Efficient in Neurons Than in Astroglial Cells

1 Induction of reactive oxygen species (ROS)/reactive nitrogen species (RNS) formation by hyperglycemia in diabetes

It significantly upregulates VEGF (vascular endothelial growth factor) expression, stimulating endothelial cell proliferation and tubule formation

Materials and methods Study design ABIS, a general population cohort consisting of 17,000 children born 1st of Oct 19971st of Oct 1999, followed prospectively with regular follow-ups