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Melatonin can promote changes in the DNA methylation of pluripotency and tissue-specific genes, leading to the improvement of the embryo developmental progress [126]

Boswood was referring to the normal LVIDDN range as high as 1.85 reported in this widely-cited 2004 article, in which its authors stated: "If the result is between 1.27 and 1.85 , the value is within the normal [95%] prediction interval for this study." (Emphasis added.) So much for the "validity" of the LVIDDN measurement