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Reference: Maher P (2005)

Recovery & Results for Biosomes Recovery There is no downtime following a B12 injection

DL of HSPNPs ranged from 7.2 0.8 to 9.5 1.1%, which is consistent with previously reported lipid based nanoparticles exhibiting drug loading below 10% 36,38

Whole cell and mitochondrial proteomics After the indicated culture conditions, cell pellets were processed as per immunoblot protocol and lysed with lysis buffer (50 mM Tris-Cl pH 7.5, 150 mM NaCl, 1 mM EDTA, 2% Triton X-100) supplemented with protease inhibitors and phosphatase inhibitors (Roche)