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A universal, continuous assay for SAM-dependent methyltransferases

(A) Schematic diagram illustrates drug administration in IPEC-J2 cells (B) The cell viability of IPEC-J2 cells was determined by CCK-8 assay

Receptors involved in the extrinsic pathway form complexes with caspase 8, triggering apoptosis though the terminal pathway, which is also associated with the intrinsic apoptotic pathway (Medema et al., 1997