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(source) Glykofrydi S, Kokkinos A, Barber TM, et al

By blocking nicotinamide N-methyltransferase , it stops niacin (NAM) and methyl groups from being siphoned off into 1-MNA

Risk factors for pernicious an anemia include: Being over the age of 60 Having a family history of the condition Having an autoimmune disorder such as pernicious anemia or autoimmune gastritis Having had gastrointestinal surgery Taking certain medications, such as proton pump inhibitors or metformin Following a vegetarian or vegan diet Having a history of alcohol abuse How can you prevent Pernicious Anemia