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Download figure Open in new tab Download powerpoint Figure 3 Working model of MET in KRAS-mutant NSCLC

10.1249/mss.0b013e31802f04c7 38 FilaM.ChojnackiC.ChojnackiJ.BlasiakJ

Its catalytic Cys residue is buried at the base of a narrow pocket, differently from the other PRDXs, which renders PRDX6 unable to dimerize through disulfide formation in the native configuration, although it can homodimerize and multimerize through hydrophobic interactions (131)

Nonresponders For all current vaccines, there is a significant population of individuals who are considered nonresponders (i.e., nonseroconverters), particularly those with an inability to mount effective B-cell responses