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Tyrosol (E) (-5.9 kcal/mol) only forms a single hydrogen bond with SER283, while its solvent-exposed position and lack of interaction in the image explain the high RMSD value (~ 3.5 )

Mechanism of cytotoxicity of anticancer platinum drugs: evidence that cis-diamminedichloroplatinum(II) and cis-diammine-(1,1-cyclobutanedicarboxylato)platinum(II) differ only in the kinetics of their interaction with DNA

And previous studies in our laboratory have shown that conversion of Cys residues into Sec residues in GPx1 and GPx4 could result in dramatic loss of the catalytic activity 15,16

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Eleven of the mAbs were directed towards either the RBD or NTD, and three reacted to S2 (Fig