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doi:10.1128/MCB.01469-07

G., Haiman, C

A.EbersG

Instead of a slimmer, leaner, more toned-looking appearance being uncovered by the loss of excess weight, they now have areas of unsightly loose skin plaguing different areas on their body

Clinical trials have demonstrated substantial weight losswith SURMOUNT obesity trials showing 1522% of body weight reduction at higher doses, while more modest losses were observed in type 2 diabetes trials