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Citicoline for the management of patients with traumatic brain injury in the acute phase: a systematic review and meta-analysis

(A) SLC7A11-targeted drugs (B) HMOX1-targeted drugs (C) G6PD-targeted drugs (D) RRM2-targeted drugs (E) HELLS-targeted drugs

50% increased risk of death (e.g., theophylline) are a group of alkaloids commonly used for their effects as mild stimulants and bronchodilators (Minor 1994)

By exploiting lipid peroxidation and iron metabolism dysregulation, ferroptosis provides a mechanism to eliminate therapy-resistant glioblastoma cells while minimizing reliance on immune system activation