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FIGURE 5 In summary, the possible adverse effects were reported in a number of recent rodent studies in which vitamin E was supplemented, as shown in Table 4

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As glycine acts as a powerful inhibitory neurotransmitter in the brain and spinal chord [108] and glycine transporters are differentially expressed throughout the CNS [109], it may be relevant for future studies of children with autism spectrum disorders to examine whether there are abnormalities in expression of glycine transporters in the CNS or in glycine transport across the choroid plexus in children with autism spectrum disorders