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In: Gibson GE, Dienel GA (eds) Handbook of neurochemistry and molecular neurobiology, 3rd edn

Biopsychosoc Med

2 2.8.3 Widely targeted metabolomics analysis Frozen tissue specimens were homogenized and extracted using ice-cold methanol:water (7:3, v/v) supplemented with isotope-labeled internal standards,followed by multi-platform LC-MS/MS analysis