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indica initiated SOD to scavenge O 2 , thus inducing a burst in H 2 O 2

Chai AB, Lam HHJ, Kockx M, Gelissen IC

unlike broad IL-5 or IL-5R blockade (which also reduce eosinophils but affect basophils somewhat and systemic eosinophils), Siglec-8 mAb would act on tissue eosinophils and mast cells without markedly suppressing other immune cells