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elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

Solvents and volatiles were removed under vacuum and the residue was purified by chromatography (ethyl acetate followed by 5-10% MeOH/DCM as a gradient elution) to obtain the desired compound IVc as a white solid (0.92 g, 48%)

In a similar study, mtDNA polymorphism analysis demonstrated that transmitochondrial cytoplasmic hybrid cells with 8701A/10398A are more closely related to the intracellular calcium dynamicity (Kazuno et al., 2006)

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*Correspondence: Patrick ODonoghue, [email protected] This article was submitted to Chemical Biology, a section of the journal Frontiers in Chemistry Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers